Comb polyelectrolytes: Synthetic and Biological

Note: Note: Special Day- Monday Pizza served at 11:45 AM
Speaker: Thomas Waigh, University of Manchester

When: February 24, 2014 (Mon), 12:00PM to 01:00PM (add to my calendar)
Location: SCI 352
Hosted by: Rama Bansil

This event is part of the Biophysics/Condensed Matter Seminar Series.

Abstract: An overview will be given of some of the research on comb polyelectrolytes performed in my group at the University of Manchester [1,2]. Specifically I will discuss the application of microrheology techniques such as particle tracking microrheology, optical coherence tomography picorheology and optical coherence tomography velocimetry to comb systems [3,4]. The development of scaling theories for polyelectrolyte comb dynamics will be discussed [5,6]. The new analysis tools will be illustrated with examples from mucins (Muc2 and Muc5AC) [7], mucins combined with polyphenols from tea, aggrecans [5,8] and polystyrene sulphonates [9,10].

Figure 1. The structure of flexible comb polyelectrolytes in semi-dilute solutions [10]. References [1] T.A.Waigh, Reports on Progress in Physics, 2005, 68, 685-742. [2] T.A.Waigh, ‘Applied Biophysics’, Wiley, 2005 and T.A.Waigh, ‘The physics of living processes’, Wiley, 2014. [3] M.Harvey, T.A.Waigh, Physical Review E, 2011, 83, 31502. [4] S.Jaradat, M.Harvey, T.A.Waigh, Soft Matter, 2012, 8, 11677. [5] A.Papagiannopoulos, T.A.Waigh, T.E.Hardingham, Faraday Discussion, 2008, 139, 337-357. [6] T.A.Waigh, A.Papagiannopoulos, Polymers, 2010, 2, 57-70. [7] P.Georgiades, P.D.A.Pudney, D.J.Thornton, T.A.Waigh, Biopolymers, 2014, 101, 4, 366. [8] A.Papagiannopoulos, T.A.Waigh, T.Hardingham, M.Heinrich, Biomacromolecules, 2006, 7, 2162-2172. [9] A.Papagiannopoulos, C.M.Fernyhough, T.A.Waigh, Journal of Chemical Physics, 2005, 123, 214904. [10] A.Papagiannopoulos, C.M.Fernyhough, T.A.Waigh, A.Radulescu, Macromol.Chem.Phys., 2008, 209, 2475-2486.