Pankaj Mehta


Professor of Physics 


Faculty of Computing and Data Science


Biological Design Center


Center for Regenerative Medicine


Boston University


Office: SCI 323

Phone: 617-358-6303


Boston University 

Department of Physics

590 Commonwealth Avenue,

Boston, MA 02139


Email: pankajm AT bu.edu


Aspiring to be the J Dilla of theoretical biophysics


Cirriculum vitae




Research Interests:


I am interested in theoretical problems at the interface of physics and biology. I want to understand how large-scale, collective behaviors observed in biological systems emerge from the interaction of many individual components -- whether it be molecules that allow cells to do complex computations, the emergence of cell fate in development, or trying to identify and explain the emergence of universal statistical behaviors in microbial ecosystems. I also have a running interest in problems at the intresection of machine learning and statistical physics. Ocassionally, usually spurred by an interesting conversation with a friend, I also work on some problems in quantum condensed matter (especially quantum dynamics and nonequilibrium phenomena). A summary of some of my thoughts on theory in biology can be found in this recent essay I wrote arguing that we need a twenty first century stastical physics of life.

I am a theoretical physicist but the group's research in quite inter-disciplinary. I am part of the new Faculty of Computing and Data Science, the BU Microbiome Initiative, BU Bioinformatics, the Center for Regenerative Medicine (CReM), and the BU Biological Design Center. To find out more about my research please look at my publications with links to pdf files. You can also check out my Google Scholar page.

Beyond science, I have a running interest in radical politics, sociology, and political economy (much of which I have learned from some wonderful teachers). Some of my writings can be found here. I am also part of the Gracie Barra Boston community.

All our recent codes can be found on our Github repository Emergent Behaviors in Biology. Older code generated by the group can be found here.



Group Members:


Krishna Rijal (Postdoc),Siqi Liu (Postdoc), Maria Yampolskaya (Graduate Student), Zhijie "Sarah" Feng (Graduate Student), Huan Souza (Graduate Student), Brock Ewing (undegrad).

Alumni:


Postdocs: Charles Fisher (Founder/CTO of machine learning start-up unlearn.AI, San Francisco, CA), Bobby Marsland (Theology Ph.D.,Pontifical University of the Holy Cross), Lauren Alex Golden (Computational Scientist at Broad Institute), Jason Rocks (AI/ML Research Scientist, Dayhoff Labs)

Graduate Students: Javad Noorbakhsh (Computational Scientist II, Broad Institute), Alex Lang (Technical Staff at Perplexity), Alexandre Day (Director of Data Science, Capital One), Ching-Hao Wang (Directon of AI/ML Engineering, GSK), Wenping Cui (KITP Fellow, UCSB; Postdoc, Princeton).

Undergrads: Joseph Sarmiego-Evans (Graduate school at Colorado Physics), Steven (Wooseok) Ahn, Maddie Dickens (NSF Graduate Fellowship, Berkeley Physics), Owen Howell (NSF Graduate Fellowship, Chicago Physics), Emmy Blumenthal (Hertz Fellow, Princeton)

Honorary Group Members: Marin Bukov (Group leader, Max Planck Institute for the Physics of Complex Systems, Dresden), Josh Goldford (Co-founder, Dayhoff Labs), Ed Reznik (MSKCC Computational Oncology Faculty)


Other Friends/Regular Collaborators of the group:


Caleb Bashor, Brian Cleary, Laertis Ikonomou, Jane Kondev, Kirill Korolev , Anatoli Polkovnikov, Sanchez Lab, David Schwab, Dries Sels, Segrè Lab, Anirvan Sengupta, Allyson Sgro, Ned Wingreen.




Videos of selected talks:


  1. Randomness, Complexity, and the Biological Frontier, ICAM Week of Science (Dec, 2023): video

  2. Towards a theory of microbial ecosystems, Imperial College Londoan Physics of Life Seminar (Dec, 2021): video

  3. Statistical Physics and Machine Learning approaches to biological networks, HHMI Workshop:4D Cellular Physiology Reimagined: Theory as a Principal Component (Sep, 2021): video

  4. Randomness, complexity, and the Biological Frontier, UCR Physics Colloquium (May, 2021): video

  5. Broad MIA Talk on Microbiomes and Metabolism with Josh Goldford, Broad Institute: Models, Inference, and Algorithms seminar (Dec, 2020): video

  6. Towards a Statistical Mechanics of Microbiomes, ICTP Workshop on Systems Biology and Molecular Economy of Microbial Communities (Dec, 2018): video

  7. Towards a Statistical Mechanics of Microbiomes, PCTS Bridging Theory and Experiment in Microbial Communities (Dec, 2018): video

  8. From Reinforcement Learning to Spin Glasses: The Many Surprises in Quantum State Preparation, PhysicsNext Workshop (Oct, 2018): video

  9. Statistical physics approaches to community ecology, KITP (Aug, 2017): video

  10. Energy, information, and computation in cells at the ICTS Winter school on quantiative biology (Dec.2015): Part 1,Part 2, Part 3

  11. Adventures at the interface of physics and Biology, KITP (Jan 2015): video

  12. Dictyostelium populations exploit noise to control collective behavior, BIRS Workshop on Stochasticity in Biochemical Reaction Networks, (Sept 2013): video


Publications:


To find out more about my research please look at my publications with links to pdf files.


Funding:


Our work is supported primarily by the NIH and the Chan Zuckerberg Initiative. We would also like to acknowledge previous support from the Simons Foundation and the Scialog:Molecules come to Life Program (run by the Research Corporation and Moore Foundation) and a Sloan Fellowship in Physics.


(Some) Popular Press:

Geonome Web
MIT Technology Review
Quanta Magazine (2014), reprinted in Wired
Quanta Magazine (2018), reprinted in Wired
Physics (2020)


Teaching:


Fall 2024: PY895:Advanced topics in Statistical Physics: RG and Disordred Systems

Spring 2023: PY580:Machine Learning for Physics

Fall 2022: PY541:Statistical Physics

Spring 2022: PY580:Machine Learning for Physics

Fall 2021: PY541:Statistical Physics

Spring 2021: PY571:Biophysics

Fall 2020: PY895:Machine Learning for Physicists

Spring 2016:  PY410: Statistical and Thermal Physics

Fall 2015: BE700-PY895: Methods and Logic in Quantitative Biology 

Spring 2013: PY 106: Elementary Physics 

Fall 2012:  PY501: Mathematical methods for Physicists

Spring 2013: PY 106: Elementary Physics