Eric R. Pinnick

Eric R. Pinnick

Graduate Student until 2011
Office: SCI, Room 509. 617-358-4370


Research Interests:

The physics of water and anesthetics in biological systems. The role of water structure and dynamics in mediating anesthetic action and biological processes. Force field development for molecular modeling and simulation.

Selected papers:

  • 08/10/10 Computational investigation of lipid hydration water of Lα 1-palmitoyl-2-oleoyl-sn-glycero- 3-phosphocholine at three hydration levels
  • 02/19/10 The potential of mean force of nitrous oxide in a 1,2-dimyristoylphosphatidylcholine lipid bilayer
  • 09/13/08 Nitrous Oxide Vibrational Energy Relaxation Is a Probe of Interfacial Water in Lipid Bilayers


B.S. Physics, University of Minnesota, Minneapolis, Minnesota USA, May 2003


I use theoretical and computational methods to explore the behavior of water and anesthetics in biological systems. My research focuses on several areas, including: how the structural and dynamical properties of water change as water approaches a biological system such as a cell membrane; how water mediates anesthetic action and biological processes; how anesthetics such as nitrous oxide (laughing gas) interact with water and hydrated biomolecules. By understanding both microscopic and thermodynamical properties of "special biological water" from a theoretical perspective, my work helps interpret experimental results and unravel the physical mechanisms that give rise to complex biophysical phenomena.

Research Scientist, Lincoln Labs