Amit Meller

Amit Meller

Affiliate Faculty (Associate Professor - ENG/BME)
Office: ERB, Room 701C. 617-358-4338


Research Interests:

Dr. Meller's research is directed toward the development of novel experimental techniques for the study of biomolecular interactions and dynamics, at the single molecule or at the single complex level. In particular, his research is focused on:

  • Employing nanopore force spectroscopy to study RNA unfolding and re-folding kinetics
  • DNA switches and transcription initiation kinetics
  • RNA helicases activity
  • Mapping of transcription factors interactions with DNA
  • Uultra fast DNA sequencing
  • Development of novel optical methods for single molecule detection in biomedical applications

Selected papers:

  • 04/16/10 Helix-Coil Kinetics of Individual Polyadenylic Acid Molecules in a Protein Channel
  • 01/20/10 Nanopore Based Sequence Specific Detection of Duplex DNA for Genomic Profiling
  • 12/20/09 Electrostatic focusing of unlabelled DNA into nanoscale pores using a salt gradient


  • Ph.D. Physics and Biophysics, Weizmann Institute of Science
  • M.Sc. Physics, Weizmann Institute of Science
  • B.Sc. Physics and Astronomy, Tel Aviv University