Stochastic feedback and the regulation of biological rhythms
Journal Article

Download PDF
Published: Saturday, August 15, 1998
Citation: Europhysics Letters, Volume 43, Pages 363-368
Link: http://iopscience.iop.org/0295-5075/43/4/363

Authors (1 total): P. C. Ivanov

Abstract: We propose a general approach to the question of how biological rhythms spontaneously self-regulate, based on the concept of "stochastic feedback". We illustrate this approach by considering at a coarse-grained level the neuroautonomic regulation of the heart rate. The model generates complex dynamics and successfully accounts for key characteristics of cardiac variability, including the 1/f power spectrum, the functional form and scaling of the distribution of variations, and correlations in the Fourier phases indicating nonlinear dynamics.