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DTSTAMP:20260815T154447Z
LAST-MODIFIED:20121116T203436Z
DTSTART:20110826T160000Z
DTEND:20110826T170000Z
UID:event835@bu.edu
URL:http://physics.bu.edu/internal/events/show/835
SUMMARY:Stochastic pause-and-translocation of molecular motors: distributio
	ns of dwell-times of kinesin and ribosome
DESCRIPTION:Featuring Debashish Chowdhury\, Indian Institute of Technology\
	, Kanpur\nHosted by: Sidney Redner\n\nPart of the Biophysics/Condensed Matt
	er Seminar Series.\n\nAbstract: Living matter is governed by the same laws 
	of physics and\n chemistry which describe the structure and dynamics of non
	-living system.\n However\, several special “processes”\, which
	 take place in living matter\,\n never occur in non-living systems. Many of
	 these processes are driven by\n molecular motors. These devices are either
	 proteins or macromolecular\n complexes which move along filamentous tracks
	 utilizing some form of input\n energy. In contrast to their macroscopic co
	unterparts\, these nano-machines\n are (i) made of soft matter\, (ii) drive
	n by isothermal engines\, (iii) far\n from thermodynamic equilibrium\, and 
	(iv) their dynamics is dominated by\n viscous forces and thermal noise. One
	 characteristic feature of their\n "directed"\, albeit noisy\, mo
	vements is an alternating sequence of pause\n and translocation. In this ta
	lk I'll discuss how important "hidden"\n informations on the 
	kinetics of such motors can be extracted from the\n statistics of the durat
	ions of pause+translocation. I'll present our\n recent results on dwell
	-time distributions of two motors\, namely\,\n a member of the kinesin supe
	rfamily and the ribosome. I'll also discuss the\n theory of collective 
	spatio-temporal organization of the motors on a\n track.
LOCATION:SCI 352\, 590 Commonwealth Avenue\, 02215
STATUS:CONFIRMED
CLASS:PUBLIC
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