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METHOD:PUBLISH
BEGIN:VEVENT
DTSTAMP:20260816T011532Z
LAST-MODIFIED:20121116T203436Z
DTSTART:20110128T170000Z
DTEND:20110128T180000Z
UID:event741@bu.edu
URL:http://physics.bu.edu/internal/events/show/741
SUMMARY:Theory of motor proteins that change the length of filaments
DESCRIPTION:Featuring Meredith Betterton\, University of Colorado\nHosted b
	y: Sidney Redner\n\nPart of the Biophysics/Condensed Matter Seminar Series.
	\n\nAbstract:\nIn cells\, motor proteins can walk with directional bias alo
	ng filaments; in some cases\, the motors can also do something to the end o
	f the filament that lengthens or shortens the filament.  This talk consider
	s the theory of this problem\, based on a few simple\ningredients: motors b
	ind to/unbind from a one-dimensional track\, move along the track\, and pro
	mote changes in track length at its end. I'll discuss the physics that aris
	es in this problem without assuming background in biology.  Crowding effect
	s can be important when multiple motors interact on the same track\, and th
	e coupled dynamics of the motors and track can show interesting new effects
	.  Under the right conditions\, coupled motor motion and filament shortenin
	g can act as a filament length sensor. In addition\, the filament may have 
	its own length-changing dynamics which can be altered by the motors. I'll d
	iscuss biological applications of this model\, particularly microtubule sho
	rtening by kinesin-8 proteins in mitotsis and the control of antiparallel m
	icrotubule overlaps by PCR1 and Xklp1 in anaphase.
LOCATION:SCI 352\, 590 Commonwealth Avenue\, 02215
STATUS:CONFIRMED
CLASS:PUBLIC
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