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VERSION:2.0
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METHOD:PUBLISH
BEGIN:VEVENT
DTSTAMP:20261020T034545Z
LAST-MODIFIED:20121116T203436Z
DTSTART:20070417T191500Z
DTEND:20070417T210000Z
UID:event69@bu.edu
URL:http://physics.bu.edu/internal/events/show/69
SUMMARY:Micromechanical study of DNA-protein interactions and chromosome st
	ructure
DESCRIPTION:Featuring John Marko\, Department of Physics and Astronomy and 
	Department of Biochemistry\, Molecular Biology and Cell Biology\, Northwest
	ern University\nHosted by: Rama Bansil\n\nPart of the Physics Department Co
	lloquia Series.\n\nI will discuss the use of micromechanical assays –
	 essentially measurements of elasticity – as methods to study how DNA
	 is organized by being folded by proteins\, ultimately into whole chromosom
	es. I will discuss studies at three scales of complexity. First\, I will pr
	esent results of single-DNA micromanipulation studies of proteins which com
	pact the chromosome in the bacterium E. coli.  Next\, I will show how simil
	ar techniques can be applied to the study of the dynamics of assembly of ch
	romatin fiber onto a single DNA molecule. Finally I will discuss experiment
	s which probe the internal organization of chromosomes isolated from dividi
	ng cells.
LOCATION: \, \, 
STATUS:CONFIRMED
CLASS:PUBLIC
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