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DTSTAMP:20260815T080556Z
LAST-MODIFIED:20121116T203436Z
DTSTART:20100128T203000Z
DTEND:20100128T213000Z
UID:event576@bu.edu
URL:http://physics.bu.edu/internal/events/show/576
SUMMARY:Physics of evolution-development 
DESCRIPTION:Featuring Dr. Paul Francois\, Rockefeller University\nHosted by
	: Sidney Redner\n\nPart of the Biophysics/Condensed Matter Seminar Series.\
	n\nAbstract: Evolution is the central theory of biology\, still it is not c
	lear if it can be used as a physical theory\, i.e. in a more predictive way
	. Recent insights have come from the new field of "evo/devo" (evolution-dev
	elopment) connecting molecular evolution to the dynamics and physics of emb
	ryonic development. I will describe a method of evolution "in silico" to ge
	nerate models of genetic networks performing specific biological functions\
	, and I will illustrate this method on the formation of two types of comple
	x spatio-temporal patterns in vertebrate embryos : somitogenesis (vertebrae
	 definition) and hox genes patterning (definition of the cellular antero-po
	sterior identity). Simple geometric models evolve in the computer and descr
	ibe well major aspects of embryonic development\, leading to experimental p
	redictions. Simulations and analytical calculations in simpler examples rev
	eal that evolution can be described as an incremental kinetic process\, pre
	dictable in some cases.
LOCATION:PRB 595\, 3 Cummington Mall\, 02215
STATUS:CONFIRMED
CLASS:PUBLIC
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