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METHOD:PUBLISH
BEGIN:VEVENT
DTSTAMP:20260826T173251Z
LAST-MODIFIED:20121116T203436Z
DTSTART:20100114T203000Z
DTEND:20100114T213000Z
UID:event569@bu.edu
URL:http://physics.bu.edu/internal/events/show/569
SUMMARY:Stochastic Models of Cell Maintenance and Tumor Progression
DESCRIPTION:Featuring Tibor Antal\, Harvard University\nHosted by: Sidney R
	edner\n\nPart of the Biophysics/Condensed Matter Seminar Series.\n\nAbstrac
	t:\nCancer is a genetic disease: it is caused by malignant (driver) mutatio
	ns accumulating in somatic tissues. What are the fundamental laws of tumor 
	progression and initiation? I first consider homeostasis in healthy epithel
	ial  tissues\, then I discuss the arrival of the first driver mutation. To 
	develop malignant cancer\, however\, several mutations are needed. Hence I 
	turn to models of tumor progression through several stages from benign tumo
	r to malignant cancer. I present experimental results on murine epidermis\,
	 clinical data on pancreatic and brain cancer\, and compare them to several
	 models with exact or approximate solutions.
LOCATION:PRB 595\, 3 Cummington Mall\, 02215
STATUS:CONFIRMED
CLASS:PUBLIC
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