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BEGIN:VEVENT
DTSTAMP:20260914T121802Z
LAST-MODIFIED:-11130T050000Z
DTSTART:20111021T160000Z
DTEND:20111021T170000Z
UID:event204@bu.edu
URL:http://physics.bu.edu/internal/events/show/204
SUMMARY:Shape Shifting: the statistical physics of protein conformational c
	hange
DESCRIPTION:Featuring Jeremy England\, MIT\nHosted by: Pankaj Mehta\n\nPart
	 of the Biophysics/Condensed Matter Seminar Series.\n\nABSTRACT - Since a p
	rotein's shape typically provides the basis forits function\, the
	 conformational rearrangements of proteins inresponse to ligand binding\, m
	utation\, and covalent modification veryoften underlie biologically importa
	nt molecular events\, whether in thenormal course of transducing a signal o
	r through deleteriousmisfolding.  A new analytical model of how struct
	ure depends onsequence enables us to examine many of these phenomena from t
	hestandpoint of statistical mechanics\, so that we may begin to predictand 
	explain specific changes in protein structure ranging fromallosteric motion
	 to the onset of aggregation disease.
LOCATION:SCI 352\, 590 Commonwealth Avenue\, 02215
STATUS:CONFIRMED
CLASS:PUBLIC
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