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VERSION:2.0
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BEGIN:VEVENT
DTSTAMP:20261027T041444Z
LAST-MODIFIED:20180409T144737Z
DTSTART:20180413T160000Z
DTEND:20180413T170000Z
UID:event1943@bu.edu
URL:http://physics.bu.edu/internal/events/show/1943
SUMMARY:"Biophysical constraints on cellular computation"
DESCRIPTION:Featuring Ching-Hao Wang\, Boston University\, Department of Ph
	ysics\n\nPart of the Biophysics/Condensed Matter Seminar Series.\n\nIn this
	 talk\, I'll first give the barest bit of biology to motivate computation t
	hrough signaling in living cells. I'll then formulate its biophysical under
	pinning with a probabilistic graphical model which is intimately related to
	 the statistical mechanics of the underlying molecular interactions. A few 
	results such as the upper bound on the computational capacity of synthetic 
	signaling system as well as its designability will be discussed. I'll also 
	demonstrate the close similarity of this formulation to the function counti
	ng theorem of perceptrons put forth by Thomas M. Cover in 1965\cite{cover19
	65geometrical}. Finally\, I'll address the challenges and limits of this fr
	amework\, especially how to place this bound on the currently available syn
	thetic networks.
LOCATION:SCI 352\, 590 Commonwealth Avenue\, 02215
STATUS:CONFIRMED
CLASS:PUBLIC
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