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VERSION:2.0
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BEGIN:VEVENT
DTSTAMP:20260905T115801Z
LAST-MODIFIED:20121116T203436Z
DTSTART:20071204T160000Z
DTEND:20071204T170000Z
UID:event189@bu.edu
URL:http://physics.bu.edu/internal/events/show/189
SUMMARY:"Shaking biomolecules with oscillating DNA layers"
DESCRIPTION:Featuring Dr. Uli Rant\, Walter Schottky Institut\, Technische 
	Universität München\n\nPart of the Biophysics/Condensed Matter Seminar Se
	ries.\n\nAbstract:  I will discuss a novel type of switchable biointerface 
	based on surface-tethered DNA molecules. By applying AC electric fields the
	 oligonucleotides are driven into oscillation while their motion is monitor
	ed in real time by fluorescence energy transfer. The molecular dynamics of 
	this electrically induced switching process are investigated in the time an
	d frequency domain. Switchable DNA layers of this kind can be used as funct
	ional elements in label-free\, chip-compatible biosensing schemes featuring
	 unprecedented possibilities. I will discuss the detection of DNA\, antibod
	ies\, and antibody fragments and demonstrate the identification of proteins
	 according to their kinetic "fingerprint".\n\nRant\, et al\, PNAS\, Vol 104
	\, p. 17364\, Oct 30\, 2007
LOCATION:PRB 595\, 3 Cummington Mall\, 02215
STATUS:CONFIRMED
CLASS:PUBLIC
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