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METHOD:PUBLISH
BEGIN:VEVENT
DTSTAMP:20260815T205940Z
LAST-MODIFIED:20171011T201159Z
DTSTART:20170919T190000Z
DTEND:20170919T210000Z
UID:event1804@bu.edu
URL:http://physics.bu.edu/internal/events/show/1804
SUMMARY:"Probing Structure-Function Relationships with Single Molecule Meth
	ods"
DESCRIPTION:Featuring Maria (Masha) Kamenetska\, Departments of Chemistry &
	 Physics\, Boston University\nHosted by: Kirill Korolev\nPoster: http://phy
	sics.bu.edu/internal//files/download/0919Kamenetska.pdf\n\nPart of the Phys
	ics Department Colloquia Series.\n\nAs matter is confined to the nanometer 
	scale\, unusual phenomena arise. The ~1 nm regime is where physics meets ch
	emistry–materials approach atomic dimensions and can no longer be describ
	ed by bulk properties. In order to understand and create devices on these s
	ize scales\, we must learn to probe the atomic structure of a single molecu
	le system while simultaneously measuring its function in ambient conditions
	. First\, I will describe our conductance and force spectroscopy measuremen
	ts on single metal-molecule-metal junctions and DNA-protein complexes to mo
	tivate the need for multi-probe measurements. We find that the geometry of 
	the metal-molecule interface affects electron transport properties in these
	 junctions and that unwinding kinetics of DNA-protein complexes can elucida
	te the effects of protein variants on gene regulation. Next\, I will discus
	s our recent measurements on synthetic polymers using a combined optical an
	d force spectroscopy setup and outline plans for future single molecule exp
	eriments.
LOCATION:SCI 109\, 590 Commonwealth Avenue\, 02215
STATUS:CONFIRMED
CLASS:PUBLIC
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