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DTSTAMP:20260825T223802Z
LAST-MODIFIED:20170405T150214Z
DTSTART:20170418T193000Z
DTEND:20170418T203000Z
UID:event1736@bu.edu
URL:http://physics.bu.edu/internal/events/show/1736
SUMMARY:Detangling the vascular web: Loops\, hierarchies\, and the quest fo
	r Nature’s design principles
DESCRIPTION:Featuring Eleni Katifori\, Penn\nHosted by: Kirill Korolev\n\nP
	art of the Physics Department Colloquia Series.\n\nLife above a certain siz
	e relies on a circulatory system for oxygen and nutrient delivery. Without 
	it\, no complex animal would exceed a few millimeters: by diffusion alone\,
	 oxygen would not be able to travel more than 100μm in the tissue. Plants\
	, animals and fungi have developed circulatory systems of striking complexi
	ty to solve the formidable problem of nutrient delivery and waste removal. 
	Typically\, biological transport networks have to satisfy competing demands
	 to operate efficiently and robustly while confronted with an ever-changing
	 environment. The architecture of these networks\, as defined by the topolo
	gy and edge weights\, determines how efficiently the networks perform their
	 function. \nIn this talk we present some general models regarding the emer
	gence\, function and quantification of biological transport networks\, from
	 the reticulate vascular architecture of the leaf\, to the hierarchies of t
	he veins and arteries in our brain. We first discuss how a hierarchically o
	rganized vascular system can develop  under constant or variable flow and s
	how how time-dependent flow can stabilize anastomoses and lead to a topolog
	y dominated by cycles. Next\, inspired by hemodynamic fluctuations in the b
	rain\, we examine how networks dynamically adapt to reroute flow to prescri
	bed network locations. Last\, we present some tools to characterize the top
	ology of cycle-rich network architectures\, such as the one found in the ma
	mmalian neocortex.
LOCATION:COM 101\, 640 Commonwealth Avenue\, 02215
STATUS:CONFIRMED
CLASS:PUBLIC
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