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VERSION:2.0
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CALSCALE:GREGORIAN
METHOD:PUBLISH
BEGIN:VEVENT
DTSTAMP:20260825T223806Z
LAST-MODIFIED:20170119T204121Z
DTSTART:20170123T180000Z
DTEND:20170123T190000Z
UID:event1700@bu.edu
URL:http://physics.bu.edu/internal/events/show/1700
SUMMARY:Dissipation\, time asymmetry\, and flux for model biomolecular syst
	ems
DESCRIPTION:Featuring Aidan Brown\, Simon Fraser University\n\nPart of the 
	Condensed Matter Theory Seminar Series.\n\nThermal fluctuations play a sign
	ificant role in biomolecular systems\, notably by preventing them from alwa
	ys proceeding in a preferred direction. With energy dissipation necessary t
	o break detailed balance\, we can ask how best to dissipate energy such tha
	t a system is driven in the preferred direction. First\, by considering a m
	odel of microscopic energy storage\, the characteristics that allow time-re
	versal symmetry to be efficiently broken at fixed energy dissipation are ex
	amined. I find that an intermediate energy barrier produces unusually high 
	asymmetry. Second\, using a biased chemical reaction cycle\, I determine ho
	w to optimize the distribution of free energy dissipation to various stages
	 of a cycle\, to maximize the rate of forward progress. My results show tha
	t the flux-maximizing distribution of dissipation depends on the inherent t
	imescales of different transition pathways\, as well as the total free ener
	gy dissipation available.
LOCATION:SCI 328\, 590 Commonwealth Avenue\, 02215
STATUS:CONFIRMED
CLASS:PUBLIC
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