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BEGIN:VEVENT
DTSTAMP:20260824T135121Z
LAST-MODIFIED:20160518T203645Z
DTSTART:20160519T160000Z
DTEND:20160519T180000Z
UID:event1610@bu.edu
URL:http://physics.bu.edu/internal/events/show/1610
SUMMARY:Why are Microbes Chiral?
DESCRIPTION:Featuring Ashish Bino George\n\nPart of the Preliminary Oral Ex
	am.\n\nExamining Committee: Kirill Korolev\, Pankaj Mehta\, Rama Bansil\, S
	teve Ahlen\n\nAbstract:\nChiral growth is common in the microbial world and
	 during embryogenesis\, but the origins of chirality remain unclear. We sho
	w that chiral mutants have a distinct selective advantage\, and the chirali
	ty at the population level is a result of natural selection rather than an 
	accidental byproduct of evolution.\n\nWe developed a minimal reaction-diffu
	sion model to describe the emergence of chiral patterns in microbial popula
	tions from the chiral behavior of individual cells. In agreement with recen
	t experiments\, the model predicts logarithmic spirals separating different
	 sub-populations in a colony. Competition between strains with different ch
	iralities typically results in the exclusion of the less chiral strain or s
	table coexistence between strains with opposite chiralities. These outcomes
	 arise from the aggregation of strains with different chiralities and the f
	aster expansion of denser aggregates. We also find that chirality promotes 
	invasion\, species intermixing\, and can stabilize mutualistic interactions
	 such as cross-feeding. Altogether\, our results suggest several mechanisms
	 that provide an advantage to chiral cells and could explain experimental o
	bservations of chirality switching in certain microbial populations and dur
	ing cancer progression. \n\n![Ashish](/resources/event-image/1610/1b0003c_o
	riginal)
LOCATION:SCI 328\, 590 Commonwealth Avenue\, 02215
STATUS:CONFIRMED
CLASS:PUBLIC
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